Genetic markers and their application in livestock breeding in South Africa: a review

The development of molecular biological techniques has created new possibilities for the selection and genetic improvement of livestock. The discovery of the PCR had a major impact on the research of eukaryotic genomes and contributed to the development and application of various DNA markers. DNA markers have already found wide application in parentage verification, individual identification and control of genetic disorders. The ultimate use of DNA markers would be to identify quantitative trait loci (QTLs) in order to practice genotypic selection. This paper reviews DNA markers (RAPD, DFP, RFLP AFLP, minisatellites, microsatellites, SNP) and provides a brief overview of the current application of these markers in animal breeding.