The reproductive efficiencies of ewes treated with the intravaginal progestagen sponge (MAP), an intravaginal progestagen sponge (MAP) followed by an injection of cloprostenol (125 μg), a double injection of 250 μg cloprostenol at a 9-day interval and a control group were compared. The oestrous response, the interval from cessation of treatment to the onset of oestrus and the duration of oestrus did not differ significantly for the respective groups. The mean conception rate of ewes treated with a double injection of cloprostenol at a 9-day interval was significantly lower (36.0%) than that of the other groups (mean 71,9%)